Protein Modification Reagents
![Medchemexpress LLC Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate) | 236754-49-7 | MFCD28505520 | 99.3% | 417.48 g/mol | C17H27N3O7S | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203782.png-250.jpg)
Medchemexpress LLC Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate) | 236754-49-7 | MFCD28505520 | 99.3% | 417.48 g/mol | C17H27N3O7S | 100 MG
Azide-PEG5-Tos is a tosyl-activated azido polyethylene glycol linker (PEG5) used as a cleavable spacer and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It contains an azide functional group for copper-catalyzed and strain-promoted azide-alkyne cycloaddition, and a tosyl leaving group for nucleophilic substitution. Supplied for research use with high purity and good DMSO solubility.
- Cleavable 5-unit PEG linker suitable for ADC and bioconjugation chemistry.
- Azide functional group enables CuAAC and SPAAC click reactions.
- Tosyl-activated for nucleophilic substitution and conjugation.
- High purity (≈99.3%).
- Soluble in DMSO at ≥100 mg/mL for convenient stock solutions.
Cayman Chemical dPE-PEG 2000-NHS 100mg
A PEGylated derivative of DSPE; has been used in the generation of micelles and in combination with other lipids in the formation of liposomes; intravenous injection of liposomes containing DSPE-PEG(2000)-NHS ester localize to mouse liver and tumor tissue; liposomes containing DSPE-PEG(2000)-NHS ester conjugated to H6 peptide and encapsulating doxorubicin reduce tumor growth in an SK-BR-3 breast cancer mouse xenograft model
Cayman Chemical BIOnT PROTAC Fragmnt lbrar 5mg
Customers are supplied with the following data package for EAch fragment purchases: • Aqueous buffer 1H NMR raw data file • Structures and physiochemical properties in an sd file • SPR Clean Screen results The parameters used in the design of the library are: • Heavy atoms ≤ 16 • clogP ≤ 3 • Hydrogen bond donors ≤ 1 • Hydrogen bond acceptors ≤ 3 • tPSA ≤ 60 • Rotatable bonds ≤ 3
Broadpharm endo-BCN-PEG4-NHS ester, 500 mg, C26H38N2O10, molecular weight 538.6 g/mol, NHS ester, BCN, DMSO/DMF/DCM soluble, amine-reactive, azide-reactive
The endo-BCN-PEG4-NHS ester is a versatile reagent specifically designed for bioconjugation applications, facilitating the labeling of biomolecules such as proteins, peptides, and oligonucleotides. With its unique functional groups, this heterobifunctional PEG derivative offers a reliable method for biomolecule modification through efficient click chemistry. Ideal for research in PROTAC synthesis and various advanced bioconjugation techniques, this product enhances solubility in aqueous environments, ensuring optimal performance in scientific applications.
- NHS ester group enables easy labeling of primary amines.
- BCN moiety allows for rapid, copper-free click reactions.
- PEG4 spacer increases solubility in aqueous media.
- Reagent grade, suitable for research purposes.
- Available quantity: 500 mg.
- Storage conditions at -20°C for stability.
- Applications include PROTAC synthesis and bioconjugation.
![eMolecules 1092654-47-1 | Azido-PEG3-CH2CO2-NHS | Broadpharm | MFCD29067172 | 330.297 | C12H18N4O7 | 98.000 | [N-]=[N+]=NCCOCCOCCOCC(=O)ON1C(=O)CCC1=O | 500mg | 393649404](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-NC2000670.JPG-250.jpg)
eMolecules 1092654-47-1 | Azido-PEG3-CH2CO2-NHS | Broadpharm | MFCD29067172 | 330.297 | C12H18N4O7 | 98.000 | [N-]=[N+]=NCCOCCOCCOCC(=O)ON1C(=O)CCC1=O | 500mg | 393649404
Azido-PEG3-CH2CO2-NHS | Broadpharm | 1092654-47-1 | MFCD29067172 | 330.297 | C12H18N4O7 | 98.000 | [N-]=[N+]=NCCOCCOCCOCC(=O)ON1C(=O)CCC1=O | 500mg | 393649404
Medchemexpress LLC 27-Norcholest-5-en-25-yn-3-ol, (3β)- | 1631985-09-5 | C26H40O | 5 MG
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization.
- It is a click chemistry reagent containing an alkyne group.
- The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst.
- It can be used for tracking cellular cholesterol metabolism and localization.
Medchemexpress LLC Dspe-peg-fitc | 95.0% | 600 Da (average) | 10 MG
Fluorescein-labeled PEGylated phospholipid supplied as a powder with an average molecular weight of approximately 600 Da. This reagent-grade fluorescent lipid conjugate is designed for incorporation into liposomes and lipid nanoparticles to enable fluorescent labeling, tracking, and imaging in laboratory research. It is supplied for research use only and can form micelles in aqueous solution.
- Fluorescent pegylated phospholipid for liposome and nanoparticle labeling.
- Average molecular weight 600 Da (average).
- Reagent grade powder suitable for research use.
- Forms micelles in aqueous solution.
- Purity 95.0% per certificate of analysis.
- Store protected from light at 4°C; in solvent store at -80°C for up to 6 months.
Medchemexpress LLC APN-C3-PEG4-azide | 2183440-32-4 | 97.97% | C24H32N6O6 | 50 MG
APN-C3-PEG4-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Medchemexpress LLC Biotin-PEG4-Amide-C6-Azide | 1006592-62-6 | 99.1% | C27H49N7O7S | 50 MG
Biotin-PEG4-Amide-C6-Azide | 1006592-62-6 | 99.1% | C27H49N7O7S | 50 MG
Medchemexpress LLC APN-PEG5-VC-PAB-MMAE | 2252392-31-5 | 95.19% | 1577.90 | 5 MG
APN-PEG5-VC-PAB-MMAE is a drug-linker conjugate that is part of INA03, a transferrin-competitive antibody-drug conjugate against CD71. It is for research use only.
- Drug-linker conjugate
- Part of INA03 (a transferrin-competitive antibody-drug conjugate against CD71)
Medchemexpress LLC Mal-PEG-mal (MW 2000) | 98.4% | 50 MG
Mal-PEG-mal (MW 2000) is a solid chemical compound primarily used as a PROTAC linker for laboratory applications and in the manufacturing of substances.
- Used as a PROTAC linker
- Suitable for laboratory chemical applications
- Suitable for substance manufacturing
- Solid appearance
- Store at -20°C, sealed, away from moisture
Medchemexpress LLC Methyltetrazine-PEG5-alkyne | 1802907-97-6 | MFCD28334550 | 98.0% | C20H26N4O5 | 10MG
Methyltetrazine-PEG5-alkyne is a PEG-based linker reagent containing a methyltetrazine moiety and a terminal alkyne, intended for bioorthogonal conjugation and PROTAC linker synthesis. Supplied as a high-purity research chemical, it is suitable for click chemistry and bioconjugation workflows and is soluble in DMSO.
- Contains methyltetrazine and terminal alkyne functional groups.
- PEG5 spacer provides flexibility and solubility.
- High purity (98.0%) for reliable experimental results.
- Soluble in DMSO for easy handling and reaction setup.
- Available in small quantities suitable for research workflows.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG20-CH2CH2COOH | 5 g | CAS 1952360-93-8 | MDL MFCD21363316
Fmoc-NH-PEG20-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1952360-93-8
- MDL: MFCD21363316
- InChIKey: YIKBHNBKAGGRHQ-UHFFFAOYSA-N
- Molecular Weight: 1192.397
- Molecular Formula: C58H97NO24
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-henicosaoxa-4-azaheptahexacontan-67-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O
Medchemexpress LLC Dopamine-PEG-N3 MW 50mg
Dopamine-PEG-N3 (MW 2000) (Dopamine-PEG-Azide (MW 2000)) is a compound composed of dopamine PEG segments and an azide group (-N3) Dopamine-PEG-N3 (MW 2000) can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials Dopamine-PEG-N3 (MW 2000) is a click chemistry reagent It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group
Medchemexpress LLC Cholesterol-PEG 600 | 69068-97-9 | <1% | 1055.60 g/mol | C68H110O8 | 250 MG
Cholesterol-PEG 600 is a cholesterol-polyethylene glycol conjugate supplied for research use, provided as an off-white to light yellow oil. It is designed to introduce cholesterol moieties into membranes or to increase water solubility of lipid-modified constructs for biochemical and formulation studies.
- Cholesterol-PEG conjugate for membrane anchoring and formulation.
- Soluble in water (~60 mg/mL) with ultrasonic and warming.
- Appearance: off-white to light yellow oil.
- Storage: store pure material at -20°C; in solvent, -80°C for long term; aliquot to avoid freeze-thaw.
- Certificate of analysis shows total cholesterol ~20.4% and free cholesterol <1%.
- Available in multiple pack sizes from milligram to gram quantities.